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The p90 Ribosomal S6 Kinase (RSK) Is a Mediator of Smooth Muscle Contractility

In the canonical model of smooth muscle (SM) contraction, the contractile force is generated by phosphorylation of the myosin regulatory light chain (RLC(20)) by the myosin light chain kinase (MLCK). Moreover, phosphorylation of the myosin targeting subunit (MYPT1) of the RLC(20) phosphatase (MLCP)...

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Detalhes bibliográficos
Main Authors: Artamonov, Mykhaylo, Momotani, Ko, Utepbergenov, Darkhan, Franke, Aaron, Khromov, Alexander, Derewenda, Zygmunt S., Somlyo, Avril V.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3596281/
https://ncbi.nlm.nih.gov/pubmed/23516539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058703
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