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The p90 Ribosomal S6 Kinase (RSK) Is a Mediator of Smooth Muscle Contractility

In the canonical model of smooth muscle (SM) contraction, the contractile force is generated by phosphorylation of the myosin regulatory light chain (RLC(20)) by the myosin light chain kinase (MLCK). Moreover, phosphorylation of the myosin targeting subunit (MYPT1) of the RLC(20) phosphatase (MLCP)...

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Bibliographic Details
Main Authors: Artamonov, Mykhaylo, Momotani, Ko, Utepbergenov, Darkhan, Franke, Aaron, Khromov, Alexander, Derewenda, Zygmunt S., Somlyo, Avril V.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3596281/
https://ncbi.nlm.nih.gov/pubmed/23516539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058703
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