Role of CAR and PXR in Xenobiotic Sensing and Metabolism

INTRODUCTION: The xenobiotic detoxification system, which protects the human body from external chemicals, comprises drug-metabolizing enzymes and transporters whose expressions are regulated by pregnane X receptor (PXR) and the constitutive androstane receptor (CAR). The progress made in a large nu...

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Main Authors: Wang, Yue-Ming, Ong, Su Sien, Chai, Sergio C., Chen, Taosheng
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593589/
https://ncbi.nlm.nih.gov/pubmed/22554043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/17425255.2012.685237
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