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Targeting xenobiotic receptors PXR and CAR in human diseases

Nuclear receptors such as the pregnane X receptor (PXR) and constitutive androstane receptor (CAR) are xenobiotic receptors regulating not only drug metabolism and disposition but also various human diseases such as cancer, diabetes, inflammatory disease, metabolic disease and liver diseases, sugges...

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Bibliografische gegevens
Gepubliceerd in:Drug Discov Today
Hoofdauteurs: Banerjee, Monimoy, Robbins, Delira, Chen, Taosheng
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4433851/
https://ncbi.nlm.nih.gov/pubmed/25463033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2014.11.011
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