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Targeting xenobiotic receptors PXR and CAR in human diseases
Nuclear receptors such as the pregnane X receptor (PXR) and constitutive androstane receptor (CAR) are xenobiotic receptors regulating not only drug metabolism and disposition but also various human diseases such as cancer, diabetes, inflammatory disease, metabolic disease and liver diseases, sugges...
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| Publicado en: | Drug Discov Today |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4433851/ https://ncbi.nlm.nih.gov/pubmed/25463033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2014.11.011 |
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