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Targeting xenobiotic receptors PXR and CAR for metabolic diseases

The pregnane X receptor (PXR) and the constitutive androstane receptor (CAR) are two closely related and liver-enriched nuclear hormone receptors originally defined as xenobiotic receptors. Recently, an increasing body of evidence suggests that PXR and CAR also have endobiotic functions that impact...

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Autors principals: Gao, Jie, Xie, Wen
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461088/
https://ncbi.nlm.nih.gov/pubmed/22889594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2012.07.003
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