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Targeting xenobiotic receptors PXR and CAR for metabolic diseases
The pregnane X receptor (PXR) and the constitutive androstane receptor (CAR) are two closely related and liver-enriched nuclear hormone receptors originally defined as xenobiotic receptors. Recently, an increasing body of evidence suggests that PXR and CAR also have endobiotic functions that impact...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3461088/ https://ncbi.nlm.nih.gov/pubmed/22889594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2012.07.003 |
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