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Role of CAR and PXR in Xenobiotic Sensing and Metabolism
INTRODUCTION: The xenobiotic detoxification system, which protects the human body from external chemicals, comprises drug-metabolizing enzymes and transporters whose expressions are regulated by pregnane X receptor (PXR) and the constitutive androstane receptor (CAR). The progress made in a large nu...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3593589/ https://ncbi.nlm.nih.gov/pubmed/22554043 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/17425255.2012.685237 |
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