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CAR and PXR: The Xenobiotic-Sensing Receptors

The xenobiotic receptors CAR and PXR constitute two important members of the NR1I nuclear receptor family. They function as sensors of toxic byproducts of endogenous metabolism and of exogenous chemicals and enhance their elimination. This unique function of CAR and PXR sets them apart from the ster...

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Main Authors: Timsit, Yoav E., Negishi, Masahiko
格式: Artigo
語言:Inglês
出版: 2006
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950246/
https://ncbi.nlm.nih.gov/pubmed/17284330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.steroids.2006.12.006
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