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CAR and PXR: The Xenobiotic-Sensing Receptors

The xenobiotic receptors CAR and PXR constitute two important members of the NR1I nuclear receptor family. They function as sensors of toxic byproducts of endogenous metabolism and of exogenous chemicals and enhance their elimination. This unique function of CAR and PXR sets them apart from the ster...

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Detalhes bibliográficos
Main Authors: Timsit, Yoav E., Negishi, Masahiko
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950246/
https://ncbi.nlm.nih.gov/pubmed/17284330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.steroids.2006.12.006
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