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CAR and PXR: The Xenobiotic-Sensing Receptors
The xenobiotic receptors CAR and PXR constitute two important members of the NR1I nuclear receptor family. They function as sensors of toxic byproducts of endogenous metabolism and of exogenous chemicals and enhance their elimination. This unique function of CAR and PXR sets them apart from the ster...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1950246/ https://ncbi.nlm.nih.gov/pubmed/17284330 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.steroids.2006.12.006 |
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