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Nuclear receptors CAR and PXR in the regulation of hepatic metabolism

1. The nuclear receptors CAR and PXR were first characterized as xenosensing transcription factors regulating the induction of phase I and II xenobiotic metabolizing enzymes as well as transporters in response to exogenous stimuli. 2. It has now become clear, however, that these receptors cross talk...

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Detalhes bibliográficos
Main Authors: TIEN, ERIC S., NEGISHI, MASAHIKO
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892216/
https://ncbi.nlm.nih.gov/pubmed/17118922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/00498250600861827
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