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A current structural perspective on PXR and CAR in drug metabolism
INTRODUCTION: Pregnane X receptor (PXR) and the constitutive androstane receptor (CAR) are two members of the nuclear receptor superfamily that play major roles in the expression of various drug metabolism enzymes and are known for their ligand promiscuity. As with other nuclear receptors, PXR and C...
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| Veröffentlicht in: | Expert Opin Drug Metab Toxicol |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6002932/ https://ncbi.nlm.nih.gov/pubmed/29757018 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/17425255.2018.1476488 |
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