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Small-molecule modulators of PXR and CAR
Two nuclear receptors, the pregnane X receptor (PXR) and the constitutive androstane receptor (CAR), participate in the xenobiotic detoxification system by regulating the expression of drug-metabolizing enzymes and transporters in order to degrade and excrete foreign chemicals or endogenous metaboli...
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| Pubblicato in: | Biochim Biophys Acta |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4975625/ https://ncbi.nlm.nih.gov/pubmed/26921498 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2016.02.013 |
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