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Small-molecule modulators of the constitutive androstane receptor
INTRODUCTION: The constitutive androstane receptor (CAR) induces drug-metabolizing enzymes for xenobiotic metabolism. AREAS COVERED: This review covers recent advances in elucidating the biological functions of CAR and its modulation by a growing number of agonists and inhibitors. EXPERT OPINION: Ex...
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| Publié dans: | Expert Opin Drug Metab Toxicol |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4469626/ https://ncbi.nlm.nih.gov/pubmed/25979168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/17425255.2015.1043887 |
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