Targeting Xenobiotic Nuclear Receptors PXR and CAR to Prevent Cobicistat Hepatotoxicity

Liver-related diseases including drug-induced liver injury are becoming increasingly prominent in AIDS patients. Cobicistat (COBI) is the backbone of multiple regimens for antiretroviral therapy. The current work investigated the mechanisms of adverse drug-drug interactions associated with COBI that...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Toxicol Sci
Main Authors: Shehu, Amina I, Zhu, Junjie, Li, Jianhua, Lu, Jie, McMahon, Deborah, Xie, Wen, Gonzalez, Frank J, Ma, Xiaochao
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2021
Teme:
Clinical and Translational Toxicology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8081023/
https://ncbi.nlm.nih.gov/pubmed/33629115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfab023
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki