Naïve pluripotency is associated with global DNA hypomethylation

Naïve pluripotent embryonic stem (ESCs) cells and embryonic germ (EGCs) cells are derived from the preimplantation epiblast and primordial germ cells (PGCs), respectively. We investigated whether differences exist between ESCs and EGCs in view of their distinct developmental origins. PGCs are progra...

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Hauptverfasser: Leitch, Harry G., McEwen, Kirsten R., Turp, Aleksandra, Encheva, Vesela, Carroll, Tom, Grabole, Nils, Mansfield, William, Nashun, Buhe, Knezovich, Jaysen G., Smith, Austin, Surani, M. Azim, Hajkova, Petra
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591483/
https://ncbi.nlm.nih.gov/pubmed/23416945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2510
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