Naïve pluripotency is associated with global DNA hypomethylation

Naïve pluripotent embryonic stem (ESCs) cells and embryonic germ (EGCs) cells are derived from the preimplantation epiblast and primordial germ cells (PGCs), respectively. We investigated whether differences exist between ESCs and EGCs in view of their distinct developmental origins. PGCs are progra...

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Bibliografiske detaljer
Main Authors: Leitch, Harry G., McEwen, Kirsten R., Turp, Aleksandra, Encheva, Vesela, Carroll, Tom, Grabole, Nils, Mansfield, William, Nashun, Buhe, Knezovich, Jaysen G., Smith, Austin, Surani, M. Azim, Hajkova, Petra
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591483/
https://ncbi.nlm.nih.gov/pubmed/23416945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2510
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