Rebuilding Pluripotency from Primordial Germ Cells

Mammalian primordial germ cells (PGCs) are unipotent progenitors of the gametes. Nonetheless, they can give rise directly to pluripotent stem cells in vitro or during teratocarcinogenesis. This conversion is inconsistent, however, and has been difficult to study. Here, we delineate requirements for...

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Hauptverfasser: Leitch, Harry G., Nichols, Jennifer, Humphreys, Peter, Mulas, Carla, Martello, Graziano, Lee, Caroline, Jones, Ken, Surani, M. Azim, Smith, Austin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757743/
https://ncbi.nlm.nih.gov/pubmed/24052943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2013.03.004
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