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The Germ Cell Determinant Blimp1 Is Not Required for Derivation of Pluripotent Stem Cells

Blimp1 (Prdm1), the key determinant of primordial germ cells (PGCs), plays a combinatorial role with Prdm14 during PGC specification from postimplantation epiblast cells. They together initiate epigenetic reprogramming in early germ cells toward an underlying pluripotent state, which is equivalent t...

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Detalhes bibliográficos
Main Authors: Bao, Siqin, Leitch, Harry G., Gillich, Astrid, Nichols, Jennifer, Tang, Fuchou, Kim, Shinseog, Lee, Caroline, Zwaka, Thomas, Li, Xihe, Surani, M. Azim
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3391686/
https://ncbi.nlm.nih.gov/pubmed/22770244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2012.02.023
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