Derivation of hypermethylated pluripotent embryonic stem cells with high potency

Naive hypomethylated embryonic pluripotent stem cells (ESCs) are developmentally closest to the preimplantation epiblast of blastocysts, with the potential to contribute to all embryonic tissues and the germline, excepting the extra-embryonic tissues in chimeric embryos. By contrast, epiblast stem c...

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Detalhes bibliográficos
Publicado no:Cell Res
Main Authors: Bao, Siqin, Tang, Walfred WC, Wu, Baojiang, Kim, Shinseog, Li, Jingyun, Li, Lin, Kobayashi, Toshihiro, Lee, Caroline, Chen, Yanglin, Wei, Mengyi, Li, Shudong, Dietmann, Sabine, Tang, Fuchou, Li, Xihe, Surani, M Azim
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2018
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752839/
https://ncbi.nlm.nih.gov/pubmed/29076502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2017.134
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