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Epigenetic reversion of postimplantation epiblast cells to pluripotent embryonic stem cells
The pluripotent state, which is first established in the primitive ectoderm cells (PE) of blastocysts, is lost progressively and irreversibly during subsequent development(1). For example, development of postimplantation epiblast from PE involves significant transcriptional and epigenetic changes, i...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3863718/ https://ncbi.nlm.nih.gov/pubmed/19816418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08534 |
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