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Epigenetic reversion of postimplantation epiblast cells to pluripotent embryonic stem cells

The pluripotent state, which is first established in the primitive ectoderm cells (PE) of blastocysts, is lost progressively and irreversibly during subsequent development(1). For example, development of postimplantation epiblast from PE involves significant transcriptional and epigenetic changes, i...

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Detalhes bibliográficos
Main Authors: Bao, Siqin, Tang, Fuchou, Li, Xihe, Hayashi, Katsuhiko, Gillich, Astrid, Lao, Kaiqin, Surani, M. Azim
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3863718/
https://ncbi.nlm.nih.gov/pubmed/19816418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08534
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