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Epiblast Stem Cell-Based System Reveals Reprogramming Synergy of Germline Factors

Epigenetic reprogramming in early germ cells is critical toward the establishment of totipotency, but investigations of the germline events are intractable. An objective cell culture-based system could provide mechanistic insight on how the key determinants of primordial germ cells (PGCs), including...

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Detalhes bibliográficos
Main Authors: Gillich, Astrid, Bao, Siqin, Grabole, Nils, Hayashi, Katsuhiko, Trotter, Matthew W.B., Pasque, Vincent, Magnúsdóttir, Erna, Surani, M. Azim
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3343665/
https://ncbi.nlm.nih.gov/pubmed/22482507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2012.01.020
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