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Histone variant macroH2A confers resistance to nuclear reprogramming

How various layers of epigenetic repression restrict somatic cell nuclear reprogramming is poorly understood. The transfer of mammalian somatic cell nuclei into Xenopus oocytes induces transcriptional reprogramming of previously repressed genes. Here, we address the mechanisms that restrict reprogra...

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Bibliografiske detaljer
Main Authors: Pasque, Vincent, Gillich, Astrid, Garrett, Nigel, Gurdon, John B
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116279/
https://ncbi.nlm.nih.gov/pubmed/21552206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.144
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