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Histone variant macroH2A confers resistance to nuclear reprogramming

How various layers of epigenetic repression restrict somatic cell nuclear reprogramming is poorly understood. The transfer of mammalian somatic cell nuclei into Xenopus oocytes induces transcriptional reprogramming of previously repressed genes. Here, we address the mechanisms that restrict reprogra...

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Detalhes bibliográficos
Main Authors: Pasque, Vincent, Gillich, Astrid, Garrett, Nigel, Gurdon, John B
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116279/
https://ncbi.nlm.nih.gov/pubmed/21552206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.144
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