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Histone variant macroH2A confers resistance to nuclear reprogramming

How various layers of epigenetic repression restrict somatic cell nuclear reprogramming is poorly understood. The transfer of mammalian somatic cell nuclei into Xenopus oocytes induces transcriptional reprogramming of previously repressed genes. Here, we address the mechanisms that restrict reprogra...

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Bibliografske podrobnosti
Main Authors: Pasque, Vincent, Gillich, Astrid, Garrett, Nigel, Gurdon, John B
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116279/
https://ncbi.nlm.nih.gov/pubmed/21552206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.144
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