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Histone variant macroH2A confers resistance to nuclear reprogramming

How various layers of epigenetic repression restrict somatic cell nuclear reprogramming is poorly understood. The transfer of mammalian somatic cell nuclei into Xenopus oocytes induces transcriptional reprogramming of previously repressed genes. Here, we address the mechanisms that restrict reprogra...

詳細記述

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書誌詳細
主要な著者: Pasque, Vincent, Gillich, Astrid, Garrett, Nigel, Gurdon, John B
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116279/
https://ncbi.nlm.nih.gov/pubmed/21552206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.144
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