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Histone variant macroH2A confers resistance to nuclear reprogramming

How various layers of epigenetic repression restrict somatic cell nuclear reprogramming is poorly understood. The transfer of mammalian somatic cell nuclei into Xenopus oocytes induces transcriptional reprogramming of previously repressed genes. Here, we address the mechanisms that restrict reprogra...

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書目詳細資料
Main Authors: Pasque, Vincent, Gillich, Astrid, Garrett, Nigel, Gurdon, John B
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116279/
https://ncbi.nlm.nih.gov/pubmed/21552206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.144
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