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Structural Characterization of the Histone Variant macroH2A

macroH2A is an H2A variant with a highly unusual structural organization. It has a C-terminal domain connected to the N-terminal histone domain by a linker. Crystallographic and biochemical studies show that changes in the L1 loop in the histone fold region of macroH2A impact the structure and poten...

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Autors principals: Chakravarthy, Srinivas, Gundimella, Sampath Kumar Y., Caron, Cecile, Perche, Pierre-Yves, Pehrson, John R., Khochbin, Saadi, Luger, Karolin
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190287/
https://ncbi.nlm.nih.gov/pubmed/16107708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.17.7616-7624.2005
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