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macroH2A1 Histone Variants Are Depleted on Active Genes but Concentrated on the Inactive X Chromosome

Using a novel thiol affinity chromatography approach to purify macroH2A1-containing chromatin fragments, we examined the distribution of macroH2A1 histone variants in mouse liver chromatin. We found that macroH2A1 was depleted on the transcribed regions of active genes. This depletion was observed o...

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Hlavní autoři: Changolkar, Lakshmi N., Pehrson, John R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489112/
https://ncbi.nlm.nih.gov/pubmed/16738309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02258-05
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