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macroH2A1 Histone Variants Are Depleted on Active Genes but Concentrated on the Inactive X Chromosome

Using a novel thiol affinity chromatography approach to purify macroH2A1-containing chromatin fragments, we examined the distribution of macroH2A1 histone variants in mouse liver chromatin. We found that macroH2A1 was depleted on the transcribed regions of active genes. This depletion was observed o...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Changolkar, Lakshmi N., Pehrson, John R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2006
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489112/
https://ncbi.nlm.nih.gov/pubmed/16738309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02258-05
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