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macroH2A1 Histone Variants Are Depleted on Active Genes but Concentrated on the Inactive X Chromosome

Using a novel thiol affinity chromatography approach to purify macroH2A1-containing chromatin fragments, we examined the distribution of macroH2A1 histone variants in mouse liver chromatin. We found that macroH2A1 was depleted on the transcribed regions of active genes. This depletion was observed o...

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Detalles Bibliográficos
Main Authors: Changolkar, Lakshmi N., Pehrson, John R.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489112/
https://ncbi.nlm.nih.gov/pubmed/16738309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02258-05
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