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Mechanism of Polymerase II Transcription Repression by the Histone Variant macroH2A
macroH2A (mH2A) is an unusual histone variant consisting of a histone H2A-like domain fused to a large nonhistone region. In this work, we show that histone mH2A represses p300- and Gal4-VP16-dependent polymerase II transcription, and we have dissected the mechanism by which this repression is reali...
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Main Authors: | , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Microbiology
2006
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1347033/ https://ncbi.nlm.nih.gov/pubmed/16428466 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.3.1156-1164.2006 |
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