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Mechanism of Polymerase II Transcription Repression by the Histone Variant macroH2A

macroH2A (mH2A) is an unusual histone variant consisting of a histone H2A-like domain fused to a large nonhistone region. In this work, we show that histone mH2A represses p300- and Gal4-VP16-dependent polymerase II transcription, and we have dissected the mechanism by which this repression is reali...

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Detalhes bibliográficos
Main Authors: Doyen, Cécile-Marie, An, Woojin, Angelov, Dimitar, Bondarenko, Vladimir, Mietton, Flore, Studitsky, Vassily M., Hamiche, Ali, Roeder, Robert G., Bouvet, Philippe, Dimitrov, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1347033/
https://ncbi.nlm.nih.gov/pubmed/16428466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.3.1156-1164.2006
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