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Dynamic equilibrium and heterogeneity of mouse pluripotent stem cells with distinct functional and epigenetic states

Embryonic stem cells (ESC) are apparently homogeneous self-renewing cells, but Stella, a marker of preimplantation embryos and germ cells showed heterogeneous expression in ESCs. Here we show that the Stella-positive ESCs were like the inner cell mass (ICM) while the Stella-negative cells were like...

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Detalhes bibliográficos
Main Authors: Hayashi, Katsuhiko, de Sousa Lopes, Susana M Chuva, Tang, Fuchou, Lao, Kaiqin, Surani, M Azim
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3847852/
https://ncbi.nlm.nih.gov/pubmed/18940731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2008.07.027
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