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Reprogramming Primordial Germ Cells into Pluripotent Stem Cells
BACKGROUND: Specification of primordial germ cells (PGCs) results in the conversion of pluripotent epiblast cells into monopotent germ cell lineage. Blimp1/Prmt5 complex plays a critical role in the specification and maintenance of the early germ cell lineage. However, PGCs can be induced to dediffe...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2567847/ https://ncbi.nlm.nih.gov/pubmed/18953407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003531 |
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