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Generation of germ cells from pluripotent stem cells in mammals

BACKGROUND: The germ cell lineage transmits genetic and epigenetic information to the next generation. Primordial germ cells (PGCs), the early embryonic precursors of sperm or eggs, have been studied extensively. Recently, in vitro models of PGC induction have been established in the mouse. Many att...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Reprod Med Biol
Hauptverfasser: Hayashi, Masafumi, Kawaguchi, Takamasa, Durcova‐Hills, Gabriela, Imai, Hiroshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5902460/
https://ncbi.nlm.nih.gov/pubmed/29692667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/rmb2.12077
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