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Generation of germ cells from pluripotent stem cells in mammals

BACKGROUND: The germ cell lineage transmits genetic and epigenetic information to the next generation. Primordial germ cells (PGCs), the early embryonic precursors of sperm or eggs, have been studied extensively. Recently, in vitro models of PGC induction have been established in the mouse. Many att...

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Podrobná bibliografie
Vydáno v:Reprod Med Biol
Hlavní autoři: Hayashi, Masafumi, Kawaguchi, Takamasa, Durcova‐Hills, Gabriela, Imai, Hiroshi
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5902460/
https://ncbi.nlm.nih.gov/pubmed/29692667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/rmb2.12077
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