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Generation of germ cells from pluripotent stem cells in mammals

BACKGROUND: The germ cell lineage transmits genetic and epigenetic information to the next generation. Primordial germ cells (PGCs), the early embryonic precursors of sperm or eggs, have been studied extensively. Recently, in vitro models of PGC induction have been established in the mouse. Many att...

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Detalhes bibliográficos
Publicado no:Reprod Med Biol
Main Authors: Hayashi, Masafumi, Kawaguchi, Takamasa, Durcova‐Hills, Gabriela, Imai, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5902460/
https://ncbi.nlm.nih.gov/pubmed/29692667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/rmb2.12077
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