Rebuilding Pluripotency from Primordial Germ Cells

Mammalian primordial germ cells (PGCs) are unipotent progenitors of the gametes. Nonetheless, they can give rise directly to pluripotent stem cells in vitro or during teratocarcinogenesis. This conversion is inconsistent, however, and has been difficult to study. Here, we delineate requirements for...

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Hlavní autoři: Leitch, Harry G., Nichols, Jennifer, Humphreys, Peter, Mulas, Carla, Martello, Graziano, Lee, Caroline, Jones, Ken, Surani, M. Azim, Smith, Austin
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757743/
https://ncbi.nlm.nih.gov/pubmed/24052943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2013.03.004
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