Naïve pluripotency is associated with global DNA hypomethylation

Naïve pluripotent embryonic stem (ESCs) cells and embryonic germ (EGCs) cells are derived from the preimplantation epiblast and primordial germ cells (PGCs), respectively. We investigated whether differences exist between ESCs and EGCs in view of their distinct developmental origins. PGCs are progra...

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Main Authors: Leitch, Harry G., McEwen, Kirsten R., Turp, Aleksandra, Encheva, Vesela, Carroll, Tom, Grabole, Nils, Mansfield, William, Nashun, Buhe, Knezovich, Jaysen G., Smith, Austin, Surani, M. Azim, Hajkova, Petra
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591483/
https://ncbi.nlm.nih.gov/pubmed/23416945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2510
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