Activation of mGluR5 and Inhibition of NADPH Oxidase Improves Functional Recovery after Traumatic Brain Injury

Traumatic brain injury (TBI) induces microglial activation, which can contribute to secondary tissue loss. Activation of mGluR5 reduces microglial activation and inhibits microglial-mediated neurodegeneration in vitro, and is neuroprotective in experimental models of CNS injury. In vitro studies als...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Loane, David J., Stoica, Bogdan A., Byrnes, Kimberly R., Jeong, William, Faden, Alan I.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Mary Ann Liebert, Inc. 2013
Gaiak:
Original Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589874/
https://ncbi.nlm.nih.gov/pubmed/23199080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2012.2589
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