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Activation of Metabotropic Glutamate Receptor Subtype mGluR1 Contributes to Post-Traumatic Neuronal Injury

The role of phospholipase C-coupled (group I) metabotropic glutamate receptors (mGluR1 and mGluR5) in post-traumatic neuronal injury was examined using rat in vivo and in vitro models. Traumatic injury to mixed neuronal/glial cultures induced phosphoinositide hydrolysis and caused neuronal death. Ph...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Mukhin, Alexey, Fan, Lei, Faden, Alan I.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6579189/
https://ncbi.nlm.nih.gov/pubmed/8815884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.16-19-06012.1996
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