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The Metabotropic Glutamate Receptor Subtype 5 (mGluR5) Mediates Sensitivity to the Sedative Properties of Ethanol

OBJECTIVE: Inbred Long-Sleep and Short-Sleep mice (ILS and ISS) were selectively bred for differential sensitivity to the sedative effects of ethanol. Lines of mice derived from these progenitors have been used to identify several Quantitative Trait Loci (QTLs) mediating Loss Of the Righting reflex...

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Autors principals: Downing, Chris, Marks, Michael J., Larson, Colin, Johnson, Thomas E.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933419/
https://ncbi.nlm.nih.gov/pubmed/20657349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e32833d8c20
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