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Metabotropic glutamate receptor 5 (mGluR5) regulation of ethanol sedation, dependence and consumption: relationship to acamprosate actions

Recent studies have demonstrated that metabotropic glutamate receptor 5 (mGluR5) antagonists decrease alcohol self-administration and suggest that the anti-craving medication, acamprosate, may also act to decrease mGluR5 function. To address the role of mGluR5 in behavioural actions of ethanol and a...

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Detalhes bibliográficos
Main Authors: Blednov, Yuri A., Harris, R. Adron
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2574715/
https://ncbi.nlm.nih.gov/pubmed/18377703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S1461145708008584
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