Metabotropic glutamate receptor 5 (mGluR5) regulates bladder nociception

BACKGROUND: Interstitial cystitis/painful bladder syndrome (IC/PBS), is a severely debilitating chronic condition that is frequently unresponsive to conventional pain medications. The etiology is unknown, however evidence suggests that nervous system sensitization contributes to enhanced pain in IC/...

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Hlavní autoři: Crock, Lara W, Stemler, Kristina M, Song, David G, Abbosh, Philip, Vogt, Sherri K, Qiu, Chang-Shen, Lai, H Henry, Mysorekar, Indira U, Gereau IV, Robert W
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369204/
https://ncbi.nlm.nih.gov/pubmed/22449017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-8-20
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