Metabotropic glutamate receptor 5 (mGluR5) regulates bladder nociception

BACKGROUND: Interstitial cystitis/painful bladder syndrome (IC/PBS), is a severely debilitating chronic condition that is frequently unresponsive to conventional pain medications. The etiology is unknown, however evidence suggests that nervous system sensitization contributes to enhanced pain in IC/...

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Main Authors: Crock, Lara W, Stemler, Kristina M, Song, David G, Abbosh, Philip, Vogt, Sherri K, Qiu, Chang-Shen, Lai, H Henry, Mysorekar, Indira U, Gereau IV, Robert W
Format: Artigo
Language:Inglês
Published: BioMed Central 2012
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369204/
https://ncbi.nlm.nih.gov/pubmed/22449017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-8-20
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