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Cocaine Decreases Metabotropic Glutamate Receptor mGluR1 Currents in Dopamine Neurons by Activating mGluR5

Midbrain dopamine neurons are important mediators of reward and movement and are sensitive to cocaine-induced plasticity. After even a single injection of cocaine, there is an increase in AMPA-dependent synaptic transmission. The present study examines cocaine-induced plasticity of mGluR-dependent c...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: Kramer, Paul F, Williams, John T
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538356/
https://ncbi.nlm.nih.gov/pubmed/25829143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2015.91
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