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Deletion of Type 2 Metabotropic Glutamate Receptor (mGluR2) Decreases Sensitivity to Cocaine Reward in Rats
Cocaine users show reduced expression of the metabotropic glutamate receptor (mGluR2), but it is not clear whether this is a predisposing trait for addiction or a consequence of drug exposure. In this study, we found that a nonsense mutation at the mGluR2 gene decreased mGluR2 expression and altered...
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| Pubblicato in: | Cell Rep |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5555082/ https://ncbi.nlm.nih.gov/pubmed/28700935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.06.046 |
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