Deletion of Type 2 Metabotropic Glutamate Receptor (mGluR2) Decreases Sensitivity to Cocaine Reward in Rats

Cocaine users show reduced expression of the metabotropic glutamate receptor (mGluR2), but it is not clear whether this is a predisposing trait for addiction or a consequence of drug exposure. In this study, we found that a nonsense mutation at the mGluR2 gene decreased mGluR2 expression and altered...

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Vydáno v:Cell Rep
Hlavní autoři: Yang, Hong-Ju, Zhang, Hai-Ying, Bi, Guo-Hua, He, Yi, Gao, Jun-Tao, Xi, Zheng-Xiong
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555082/
https://ncbi.nlm.nih.gov/pubmed/28700935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.06.046
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