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Metabotropic glutamate receptor 5 (mGluR5) antagonists attenuate cocaine priming- and cue-induced reinstatement of cocaine seeking

Accumulating evidence suggests that metabotropic glutamate receptors (mGluRs) are involved in both cocaine reinforcement and the reinstatement of cocaine-seeking behavior. In the present experiments, rats were trained to self-administer cocaine under fixed ratio (for cocaine priming-induced reinstat...

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Detalhes bibliográficos
Main Authors: Kumaresan, Vidhya, Yuan, Menglu, Yee, Judy, Famous, Katie R., Anderson, Sharon M., Schmidt, Heath D., Pierce, R. Christopher
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844436/
https://ncbi.nlm.nih.gov/pubmed/19463707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2009.03.039
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