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Role of mGluR5 Neurotransmission in Reinstated Cocaine-seeking

In animal models of addiction, reducing glutamate stimulation of the metabotropic glutamate receptor 5 (mGluR5) inhibits drug-seeking. The present study used the reinstatement model of cocaine-seeking to show that blockade of mGluR5 directly in the core subcompartment of the nucleus accumbens (NAcor...

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Bibliographic Details
Main Authors: Wang, Xiusong, Moussawi, Kahled, Knackstedt, Lori, Shen, Haowei, Kalivas, Peter W.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360124/
https://ncbi.nlm.nih.gov/pubmed/22340009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1369-1600.2011.00432.x
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