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The Metabotropic Glutamate Receptor Subtype 5 (mGluR5) Mediates Sensitivity to the Sedative Properties of Ethanol

OBJECTIVE: Inbred Long-Sleep and Short-Sleep mice (ILS and ISS) were selectively bred for differential sensitivity to the sedative effects of ethanol. Lines of mice derived from these progenitors have been used to identify several Quantitative Trait Loci (QTLs) mediating Loss Of the Righting reflex...

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Bibliographic Details
Main Authors: Downing, Chris, Marks, Michael J., Larson, Colin, Johnson, Thomas E.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933419/
https://ncbi.nlm.nih.gov/pubmed/20657349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e32833d8c20
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