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Putative mGluR4 Positive Allosteric Modulators Activate G(i)-Independent Anti-Inflammatory Mechanisms in Microglia
Chronic dysregulated microglial activation may lead to persistent inflammation and progressive neurodegeneration. A previous study reported that ADX88178, a putative metabotropic glutamate receptor 4 (mGluR4) positive allosteric modulator (PAM), exerts anti-inflammatory effects in microglia by activ...
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| Veröffentlicht in: | Neurochem Int |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7392812/ https://ncbi.nlm.nih.gov/pubmed/32454165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuint.2020.104770 |
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