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Engineering allosteric control to an unregulated enzyme by transfer of a regulatory domain
Allosteric regulation of protein function is a critical component of metabolic control. Its importance is underpinned by the diversity of mechanisms and its presence in all three domains of life. The first enzyme of the aromatic amino acid biosynthesis, 3-deoxy-D-arabino-heptulosonate 7-phosphate sy...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3568362/ https://ncbi.nlm.nih.gov/pubmed/23345433 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1217923110 |
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