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Exploring modular allostery via interchangeable regulatory domains

Most proteins comprise two or more domains from a limited suite of protein families. These domains are often rearranged in various combinations through gene fusion events to evolve new protein functions, including the acquisition of protein allostery through the incorporation of regulatory domains....

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Fan, Yifei, Cross, Penelope J., Jameson, Geoffrey B., Parker, Emily J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866569/
https://ncbi.nlm.nih.gov/pubmed/29507215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1717621115
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