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Exploring modular allostery via interchangeable regulatory domains

Most proteins comprise two or more domains from a limited suite of protein families. These domains are often rearranged in various combinations through gene fusion events to evolve new protein functions, including the acquisition of protein allostery through the incorporation of regulatory domains....

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Fan, Yifei, Cross, Penelope J., Jameson, Geoffrey B., Parker, Emily J.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866569/
https://ncbi.nlm.nih.gov/pubmed/29507215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1717621115
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