Synergistic Allostery, a Sophisticated Regulatory Network for the Control of Aromatic Amino Acid Biosynthesis in Mycobacterium tuberculosis

The shikimate pathway, responsible for aromatic amino acid biosynthesis, is required for the growth of Mycobacterium tuberculosis and is a potential drug target. The first reaction is catalyzed by 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase (DAH7PS). Feedback regulation of DAH7PS activity b...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Webby, Celia J., Jiao, Wanting, Hutton, Richard D., Blackmore, Nicola J., Baker, Heather M., Baker, Edward N., Jameson, Geoffrey B., Parker, Emily J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2010
Soggetti:
Enzymology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945551/
https://ncbi.nlm.nih.gov/pubmed/20667835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.111856
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi