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Quaternary structure is an essential component that contributes to the sophisticated allosteric regulation mechanism in a key enzyme from Mycobacterium tuberculosis

The first enzyme of the shikimate pathway, 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (DAH7PS), adopts a range of distinct allosteric regulation mechanisms in different organisms, related to different quaternary assemblies. DAH7PS from Mycobacterium tuberculosis (MtuDAH7PS) is a homotetram...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Jiao, Wanting, Blackmore, Nicola J., Nazmi, Ali Reza, Parker, Emily J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5493349/
https://ncbi.nlm.nih.gov/pubmed/28665948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180052
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