Synergistic Allostery, a Sophisticated Regulatory Network for the Control of Aromatic Amino Acid Biosynthesis in Mycobacterium tuberculosis

The shikimate pathway, responsible for aromatic amino acid biosynthesis, is required for the growth of Mycobacterium tuberculosis and is a potential drug target. The first reaction is catalyzed by 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase (DAH7PS). Feedback regulation of DAH7PS activity b...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Webby, Celia J., Jiao, Wanting, Hutton, Richard D., Blackmore, Nicola J., Baker, Heather M., Baker, Edward N., Jameson, Geoffrey B., Parker, Emily J.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2010
Предметы:
Enzymology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945551/
https://ncbi.nlm.nih.gov/pubmed/20667835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.111856
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы